The Assessment of Cardiovascular Risk in Renal Transplant Recipients
Zbigniew Heleniak1, Karolina Komorowska-Jagielska1, Alicja Dębska-Ślizień1.
1Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, Gdansk, Poland
Introduction: The cardiovascular diseases are the most common cause of death in patients with chronic kidney disease (CKD), including patients after kidney transplantation.
Aim: The retrospective analysis of cardiovascular (CV) risk in renal transplant recipients (RTRs).
Methods: The analysis of CV risk was made based on scales: QRISK (assessment of development CV disease), Pol-SCORE (assessment of CV death) during 10 years.
Material: 100 RTRs, (M-65/F-35), transplanted in 2007-2009, in the average age 48.4 years were enrolled to the study.Coronary heart disease and diabetes were diagnosed in 7% and 15% of participants, respectively. Coronarography was performed in 38% of patients. Hypertension was diagnosed in 98% of participants, 6% and 2% of them experienced myocardial infarction and stroke, respectively.
Results: The highest risk of the CV endpoint according to the QRISK and Pol-SCORE scales was in 41%, and 41% patients, respectively. After 5 years of follow up total of 13 CV events (myocardial infarction, stroke) in 11 patients were observed. Among these patients, the highest risk of endpoint according to QRISK and Pol-SCORE scales was in 36% and 45% of patients, respectively.
Conclusions: 1. In 41% of RTRs a significant risk of CV endpoint according to QRISK and Pol-SCORE scales were assessed.2. After 5 years of follow up in RTRs, CV events occurred in 11% of patients. 3. The Pol-SCORE scale seem to be more useful tool for assessment of CV risk in RTRs in Poland.