Donation and Procurement Posters

Monday July 02, 2018 from 16:30 to 17:30

Room: Hall 10 - Exhibition

P.623 Argentine survey on the current situation of renal transplantation living donor

Rafael A Maldonado, Argentina

HEAD OF SERVICE
NEPHROLOGY AND TRANSPLANTATION SERVICE
CLINICA PRIVADA VELEZ SARSFIELD

Abstract

Argentine Survey on the Current Situation of Renal Transplantation Living Donor

Rafael Maldonado1.

1Nephrology and Transplantation Service, Clinica Privada Velez Sarsfield, Cordoba, Argentina

ARGENTINE LIVING DONOR SURVEY.

Introduction: Living Donor Renal Transplantation in the  world has presented a considerable increase in the last 5 years especially in United States, in the development of specific programs that stimulate donation for groups that had low donation rate as Hispanic Americans trying to make up for the degree of imbalance with the development of  increase in the waiting lists of chronic kidney disease in hemodialysis population. Argentina and Latin America in the world are not the exception.  The promotion of the living donation plays a fundamental role in order to reduce the persistence on the waiting list, mortality and improve their skill transplant level.
Material and Methods: In June 2016 a survey was developed whose main objective was to know the real situation of living donor kidney transplantation in Argentina. This survey was carried out by 28 centers authorized in kidney transplant by the INCUCAI the national procurement regulatory entity in Argentina represents a 49.12% (28/57).
Results: 32  professional were represented by 93.7% by nephrologists. Related with the annual number of LDRT the  majority 12 transplant center perform between 7 to 10 transplants/year (42.9 %),  11 to 20 transplants/year (25% ),  21 to 30 transplant /year (14.3%)and  more than 31 transplant/year 3.6% . Related to educational information of potential donors were performed in 67.9% the education of potential donors. Most centers expressed no precise age limit to be LD (68%), others expressed 65 years as maximum limit to donate (18%).  Excluded comorbidities: Diabetes Mellitus, Obesity (BMI ≻35), eGFR ≺80ml/min,  proteinuria  ≻300 mg/day and mental retardation. Hypertension was defined as exclusion criteria only in 9 centers representing the 4.35%. Hypertension excludes the donor when: HTA with target organ damage (32.1%), HTA with more than one drug and uncontrolled (25%) or HTA with more than one drug 17.9% or borderline HTA by ABPM (17.9%) The GFR analysis of living donor  was performed in 78.57% with serum creatinine and  24hs urine creatinine clearance. The eGFR formulas as MDRD or CKD-EPI referred a low use and Iothalamate clearance as the gold standard technique only in 7.14%.The exclusion criteria in relation to GFR was  ≺80 ml/min in 71.43%, ≺90 ml/min in 21.43%.  The glucose intolerance detection was carried out in 60.7% of the donors.
Conclusion: education in ESRD  in dialysis and the relatives were homogeneous but not enough. The criteria for selection and exclusion of donors are largely clear but with great flexibility of the risk factors analysis.  The evaluation of GFR in the selection process of LD with studies of greater sensitivity and specificity is essential to identify the risk population. The development of new stimulation programs of living donation is essential to reduce the time on the waiting list in developing countries.

 



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