Introduction: The aim of this study is to present our experience in renal transplantation recipients (RTR) and liver transplantation recipients (LTR) during cesarean section.
Materials and Methods: Retrospective data regarding renal transplantation recipients and liver transplantation recipients who underwent cesarean section at Baskent University Hospital in Ankara between January 1997 and January 2017 have been collected from hospital records.
Results and Discussion: Fourteen live births occurred from five LTRs and nine RTRs, all of them from C/S. The mean maternal age (28.4±4.1 years vs 29.2±4.1 years, p=.38), body weight before conception (57.4±8.8 kg vs 64.5±8.2 kg, p=.48) and the time from transplantation to conception (99.0±50.7 months vs 101.0±57.5 months, p=.46) were similar respectively for LTRs and RTRs.
All recipients were maintained on cyclosporine, azathioprine, tacrolimus and corticosteroids before and during pregnancy for immunosuppression. Four C/Ss were performed under general anesthesia (1 LTR vs 3 RTRs, p>.05) whereas spinal anesthesia was used in 10 patients. Liver and renal function tests were stable in all of the patients and we did not observe any acute or subacute rejection. Only one mother with renal transplantation died in one year after delivery.
The mean birth weight was similar (2502 ± 311 gr vs 2161±658 gr, p=.3). There were 3 premature vs 6 premature and low birth weight (<2500 gr) 2 vs 4 among 14 newborns. Infants small for gestational age were diagnosed in 9/14 (3 LTRs vs 6 RTRs, p=1). None of the neonates died.
Conclusion: General and regional anesthesia can be safely used during cesarean delivery of the LTRs and RTRs without increased risk of graft loses. Prematurity and low birth weight was mainly due to the cytotoxic drugs for immunosuppression. There are no differences in LTRs and RTRs for maternal and fetal complications due to in our data.