Background: Over last 13 years there were 193 pancreas transplantations performed at the Department of Gastroenterological Surgery and Transplantation at the Central Clinical Hospital of the Ministry of the Interior in Warsaw. The influence of peritoneal dialysis on SPK results is still vague. Higher risk of infectious complications and higher mortality rates in SPK patients after peritoneal dialysis is not unambiguously confirmed.
Aim: The aim of the study was to verify if type of dialysis determined outcomes of pancreas transplantation and if it was a risk factor for transplantectomy or recipient’s death. Material and Methods We analyzed a group of 91 patients after pancreas transplantations. 67% were SPK, 25% PTA, 11% PAK and 4 retransplantations. 57% of the patients were males.
Results: There were 15 (16,5%) transplantectomies in the group. The overall mortality of the group was 5,5%. Among SPK patients, there were 6 of the recipients, who were transplanted preemptively, 24 after hemodialysis, 8 after peritoneal dialysis. In the subgroup of preemptive SPK, there was one transplantectomy and one death. In the subgroup of hemodialysis the mean period of renal replacement therapy was 25 months. There were 3 graftectomies in the subgroup and 3 deaths. In the last subgroup, peritoneal dialysis, there were no graftectomies and one deaths. There were no significant differences in number of transplantectomies and mortality between three groups.
Discussion: Our study proved that type of dialysis does not influence outcomes of pancreas transplantation. Hemodialysed patients are more often characterized by vascular complications. On the other hand, peritoneal patients more often have abdominal inflammations due to chronic bacterial contamination. Each patient after pancreas transplantation requires individual treatment. Type of dialysis should not be a contradiction for transplantation.