Potential Effect of Using ABO-Compatible Living-Donor Liver Transplantation
Eleazar Chaib1, Cristina Friedman Dr1, Eduardo E Massad Dr1.
1Gastroenterology, University of Sao Paulo School of Medicine, Sao Paulo, Brazil
Liver transplantation increased 1.84 f, the number o patients on the waiting list for a liver increased 2.71 fold,old from 1988 to 2004. However, the number of patients on the waiting list for a liver increased 2.71 fold, from 553 to 1500. We used a mathematical equation to analyse the potential effect of using ABO-compatible living-donor liver transplantation (LDLT) on both our liver transplantation program and the waiting list. We calculated the prevalence distribution of blood hgroups (O,A,B and AB) in the population and the probability of having compatible parent or sibling for LDLT. The incidence of ABO compatibility in the overall population was as follow: A,mo.31; B, o.133; O, 0,0152 and AB,0.04. The ABO compatibility for parents donors was blood group A, 0.174; B, 0.06; O, 0.152 and AB, 0,03; and for sibling donor was A,0.121; B,0.05; O, 0.354 and AB, 0.03. Usew of LDLT can reduce the pressure on our liver transplantation waiting list by decresing its size by at least 16.5% at 20 years after inbtroduction.Sucha a program could save an estimated 3.600 lives over the same period.